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Leukemia

TYPES CAUSES SYMPTOMS DIAGNOSIS STAGES TREATMENT

Staging

Because leukemia starts in the bone marrow and often has spread to other organs by the time it is detected, there is no need for traditional staging. All leukemias are classified according to their genotypes, or their unique chromosomal arrangements, which also enables the physicians to determine risk factors.

Acute leukemia is classified in the French- American- British (FAB) system based upon the microscopic appearance of leukemia cells. According to FAB classification, acute leukemia is divided into eight subtypes of acute myelogenous leukemia (AML) and three subtypes of acute lymphocytic leukemia (ALL).

Chronic lymphocytic leukemia (CLL) is classified by 2 different staging systems, known as RAI Classification and Binet Staging, both based on the parts of the body affected by the leukemia.

The main features of Rai Classification stage of the chronic lymphocytic leukemia are :

  • Stage 0 - This stage have high lymphocytes (a type of WBC) count in the blood, but there are no other symptoms of leukemia. It is a slow-growing stage and patients are at low risk.
  • Stage 1 - Lymph nodes are larger than normal because of high lymphocytes count. Patients are at intermediate risk
  • Stage 2 - Lymph nodes, liver and spleen are larger than normal as a result of an overabundance of lymphocytes. Patients are at intermediate risk
  • Stage 3 - Anemia has developed because there are too few red blood cells in the blood. Lymph nodes, spleen and liver may be swollen because of high lymphocytes count. Patients are at high risk
  • Stage 4 - There are too few platelets in the blood. Lymph nodes, spleen and liver may be swollen. Anemia may be present.

Binet staging system classifies CLL according to which lymphoid tissues, such as the spleen or lymph nodes, are involved as well as the presence of low red blood cell count (anemia) or low number of blood platelets (thrombocytopenia). The major advantage of the Binet system is its ability to highlight the splenic form of CLL.

The stage of binet system are :

  • Stage A - There are three or fewer areas of enlarged lymph tissue. Lymph nodes in one particular area, such as the neck or underarm, are considered one group, whether they occur on just one side of the body (unilateral) or on both sides (bilateral).
  • Stage B - There are more than three areas of enlarged lymph tissue.
  • Stage C - Enlarged lymph tissue is present along with anemia and thrombocytopenia.



Viewer's Comment
 pravesh jain, Delhi    21/10/2013
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Questions of
 Questions & Answers
 1.  Posted on : 16.1.2015  By  :  Mitali , Delhi View Answer (0) Post Answer
 

My husband is suffer from blood cancer.. He had his first stage.. He took very expensive treatment by still he suffers a lot on his disease..... Is dis possible dat he can be became fit???

 
 2.  Posted on : 23.5.2013  By  :  Dharmendra Kumar Singh , Kolkata View Answer (2) Post Answer
 

My nephew age 3+ has blood cancer 1st stage, please sugest me low budget hosital in Kolkata.

 
A1: 

The cheapest Hopital for Cancer treatment is Tata Medical at Rajarhat. It is the best in Eastern Region.

  Posted By :Subho , kolkata | On 11.6.2013
A2: 

There is a lot of cancer research is going on at tata cancer centre. You could try there.

  Posted By :Admin , Kochi | On 23.5.2013
 3.  Posted on : 16.8.2012  By  :  Payalkelkar , Nagpur View Answer (1) Post Answer
 

Suggest best treatment for blood cancer 1st stage, and best hosital in nagpur.

 
A1: 

You should be under the care of an Oncologist and follow his adivice. https://yellowpages.webindia123.com/dpy/Maharashtra/Nagpur/Hospitals/1/

  Posted By :Admin , Kochi | On 4.6.2013
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