Female Infertility
Causes
Most women have no obvious signs of infertility until they
try to become pregnant and are not successful after one year. Infertility may
sometimes be signaled by heavy, irregular or absent menstrual periods or associated
with conditions that cause pain during menstruation or intercourse. Other signs
that may point to fertility problems include obesity, facial hair and fluid
that leaks from the breasts.
Infertility problem may occur by various reasons. The
most common cause of female infertility include ovulation disorders, polycystic ovarian
syndrome, fallopian
tube damage or blockage, endometriosis,
ovarian cysts, fibroids, pelvic infection and early menopause. It may also be caused by
sexually transmitted diseases, poor nutrition, hormone imbalance, tumor, uterine
factors and egg quality.
Ovulation disorders
Ovulation problems result when one part of the system that controls reproductive
function malfunctions. The failure to ovulate is the most common cause of female
infertility. Without ovulation, eggs are not available to be fertilized. Ovulation
problems can be caused by various things such as excessive weight loss, stress,
thyroid problems or slight irregularities in hormone imbalances. Disruption
in the part of the brain that regulates ovulation (hypothalamic-pituitary axis)
can cause deficiencies in luteinizing hormone (LH) and follicle-stimulating
hormone (FSH). Signs of problems with ovulation include irregular menstrual
periods or no periods.
Polycystic Ovarian Syndrome (PCOS)
Polycystic ovarian syndrome is a condition characterised by the presence
of many minute cysts in the ovaries which is caused by excess production of
hormone called androgen. This will prevent the follicles of the ovaries from
producing a mature egg. Without egg production, the follicles swell with fluid
and form into cysts. Every time an egg is trapped within the follicle, another
cyst forms, so the ovary swells, sometimes reaching the size of a grapefruit.
PCOS can be diagnosed through a series of blood tests and some symptoms of this
condition include weight gain, acne, irregular or absent periods.
Fallopian tube damage or blockage
This condition usually results from inflammation of the fallopian tube (salpingitis).
If they are blocked, the egg cannot move from the ovary to the uterus. This
condition can happen as a result of pelvic inflammatory disease, endometriosis,
pelvis surgery, ruptured appendix or mislocated (ectopic) pregnancy. Structural
disorders, like birth defects of the uterus and fallopian tubes, fibroids in
the uterus, and bands of scar tissue can also block the fallopian tubes.
Endometriosis
This is a condition when the tissue that makes up the lining of the uterus
(endometrium) grows into growths or lesions outside of the uterus usually on
the ovaries or the lining of the abdomen near the uterus and fallopian tubes.
In sync with the menstrual cycle, this tissue builds up, breaks down and sheds
each month; but it has no way of leaving the body. As a result it causes internal
bleeding, breakdown of blood which can lead to scarring and inflammation.
Pelvic pain and infertility are common in women with endometriosis. It can be
detected during laparoscopy. If you experience pain while having sex, have very
painful menstrual cramps, or experience heavy bleeding during your period or
unusual spotting, you may have endometriosis.
Ovarian Cysts (Endometriomas)
Ovarian cysts may indicate advanced endometriosis and often is associated
with reduced fertility. An ovarian cyst is a small fluid-filled sac that grows
in the ovary. Endometriomas can be treated with surgery.
Uterine Fibroids
Uterine fibroids or leiomymomas are benign tumors usually located on the
outside surface or within the muscular wall of the uterus. They are not associated
with the reproductive system but may cause infertility by interfering with the
contour of the uterine cavity, blocking the fallopian tubes. It can also interfere
with embryo implantation or fetal growth. Though the causes of these tumors
are unknown, evidence suggest that estrogen and progesterone contribute to the
growth of fibroids. It is most often diagnosed in women between the ages of
30 and 40. Common symptoms of fibroids is pelvic pressure, along with irregular
bleeding and the effective treatment option is hysterectomy.
Premature Ovarian Failure (POF) or Early Menopause
Early menopause is the absence of menstruation and the early depletion of
ovarian follicles before age 40. Though the cause is often unknown, the condition
is associated with autoimmune disease, pelvic surgery, tobacco smoking, genetic
factors, radiation or chemotherapy. Treatment option for POF is In Vitro
Fertilization (IVF).
Pelvic Inflammatory Disease (PID)
PID is an infection of the pelvis or organs of the reproductive tract, including
the ovaries, the fallopian tubes, the cervix or the uterus. It can lead to blocked
or damaged fallopian tubes and is usually caused by
sexually transmitted diseases,
miscarriages, abortions, childbirth, or an intrauterine device.
Pelvic Adhesions
Pelvic adhesions are bands of scar tissue formed between two or more internal
organs after pelvic infection, appendicitis or abdominal or pelvic surgery.
This condition is usually caused by surgery or infection and can affect the functioning
of the ovaries and fallopian tubes resulting in infertility.
Age is also a risk factor of infertility. A woman's
peak fertility occurs in her early 20s. The ability for ovaries to produce eggs
declines with age, especially after age 35. As a woman ages beyond 35 (and particularly
after age 40), the likelihood of conceiving diminishes to less than 10% per
month. The risk of miscarriage also increases with a woman's age. Tobacco smoking,
alcohol consumption, extremes in body mass either too high or too low are all
risk factors of infertility.
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