The Mahatma Gandhi Road (M.G road) earlier known as the Seventy-feet Road, branches off from Banerji Road in its north end right up to Thevara Junction down south covering approximately four kilometers. M.G. Road is today the city's main commercial centre housing retail shops selling all kind of goods such as textiles, ready made garments,  jewellery, toys, home furnishing, handicrafts, decorative items etc. Outlets of International Ready to Wear brands such as Van Heusen, Arrow, Lee, Bennetton, Allen Solly, Louis Philippe and leading Indian brands such as Park Avenue are located on this road. Raymonds and Only Vimal are good places to buy suit lengths. For casuals, Graffiti at Hotel Abad Plaza is a good option with reasonable prices. For large collection of  ready-mades and textiles for the whole family including sarees, salwars etc visit Seematti, at the northern end, Jayalakshmi and Parthas near Jos Junction on the MG road.

M.G. Road also has some excellent jewellery shops selling both traditional, ethnic and modern jewellery. Allapattu House, Alukkas, Josco and Bhima here are some of the largest showrooms. Bata, Boots and Woodlands on M.G. road and Mesco's in Jos junction are good places to buy shoes. The Kerala State Handicrafts Development Corporations Showroom Kairali and Kathais near Jos Junction and Khadi Bhavan, have excellent collection of handicrafts and Khadi products including pure Khadi cotton and silk, Kolhapuri Chappals etc. respectively. Convent Road, branching westwards from the MG road, has a growing number of exclusive boutiques and outlets for the trendy and brand-conscious. The Esplanade building in the convent junction has showrooms selling ready to wear International brands. Besides the shopping malls, MG road has a number of hotels and restaurants and Cinema halls for entertainment.